{"id":14735,"date":"2026-02-10T11:23:00","date_gmt":"2026-02-10T14:23:00","guid":{"rendered":"https:\/\/pipaufrj.me.ufrj.br\/?p=14735"},"modified":"2026-02-10T11:23:00","modified_gmt":"2026-02-10T14:23:00","slug":"exposicao-materno-fetal-a-metais-de-interesse-a-saude-publica-em-area-urbana-2","status":"publish","type":"post","link":"https:\/\/pipaufrj.me.ufrj.br\/en\/exposicao-materno-fetal-a-metais-de-interesse-a-saude-publica-em-area-urbana-2\/","title":{"rendered":"Maternal-fetal exposure to metals of public health interest in an urban area"},"content":{"rendered":"
\n\t\t\t\t
\n\t\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\n\t\t\t

Introduction:<\/strong> A exposi\u00e7\u00e3o ambiental a metais em \u00e1reas urbanas tem sido associada a desfechos do nascimento tais como: prematuridade, baixo peso ao nascer e baixo \u00edndice de Apgar. Para avaliar a exposi\u00e7\u00e3o pr\u00e9-natal a poluentes ambientais em \u00e1rea urbana, foi realizado um estudo piloto, componente do corpo de estudos e pesquisas que comp\u00f5em a coorte de nascimentos denominada \u201cEstudo longitudinal dos efeitos da exposi\u00e7\u00e3o a poluentes ambientais sobre a sa\u00fade infantil\u201d \u2013 Projeto Inf\u00e2ncia e Poluentes Ambientais (PIPA).<\/p>

Objective:<\/strong> To assess exposure to metals of public health interest\u2014arsenic (As), cadmium (Cd), lead (Pb), and mercury (Hg)\u2014in newborns in an urban area of the Municipality of Rio de Janeiro.<\/p>

Methods:<\/strong> From October and November 2017, all pregnant women cared for at ME-UFRJ, over 16 years of age, were invited to participate in the project. The following were collected: 1) socioeconomic, cultural, leisure, and living condition information from the parents 2) Maternal blood 3) Umbilical cord blood, newborn anthropometric data, and APGAR scores.<\/p>

Results:<\/strong> Das 209 gestantes abordadas, 142 aceitaram participar (67,9%). De outubro\/2017 a fevereiro\/2018 houveram 131 nascimentos (92,3%) foram avaliados as amostras de sangue materno (sm) e sangue do cord\u00e3o umbilical (scu)de 117 pares de m\u00e3e e bebe. Houve correla\u00e7\u00e3o entre as concentra\u00e7\u00f5es de As, Cd, Pb e Hg no sm e no scu (rAs= 0,71, p < 0,0001; rCd= 0,61, p < 0,0001; rPb= 0,67, p <0,0001; rHg= 0,70, p <0,0001). N\u00e3o foi encontrada correla\u00e7\u00e3o entre a concentra\u00e7\u00e3o de metais no sm e as vari\u00e1veis idade materna, renda e anos de estudo, n\u00e3o houve diferen\u00e7a significativa entre as concentra\u00e7\u00f5es dos metais no sm e as vari\u00e1veis de exposi\u00e7\u00e3o relacionadas \u00e0 moradia, exposi\u00e7\u00e3o ao tabaco e consumo de bebida alco\u00f3lica. Houve diferen\u00e7a estatisticamente significativa para a concentra\u00e7\u00e3o de Cd no sm e o consumo de leguminosas (p< 0,03), reforma da casa durante a gesta\u00e7\u00e3o (p < 0,02) e ra\u00e7a, sendo maior na ra\u00e7a n\u00e3o branca (p<0,025). As medianas de Pb no sm (3,75 \u00b5g\/dL) e no scu (3,69 \u00b5g\/dL) foram maiores neste estudo do que em outros realizados no Brasil e no mundo, 25% da nossa popula\u00e7\u00e3o de estudo apresentou concentra\u00e7\u00e3o de Pb no scu maior do que 5 \u00b5g\/dL, valor estabelecido pelo \u201cCenters for Disease Control and Prevention\u201d (CDC) como ponto de corte para exposi\u00e7\u00e3o de crian\u00e7as . N\u00e3o houve correla\u00e7\u00e3o entre a concentra\u00e7\u00e3o de Pb no scu e os desfechos do nascimento avaliados (peso, prematuridade e Apgar).<\/p>

Conclusion:<\/strong> Blood Pb concentration is a biomarker of exposure; since values above the reference established by the CDC were found in this study, it is necessary to investigate possible sources of lead exposure and its effects on child development.<\/p>

Keywords:<\/strong> Arsenic. Cadmium. Lead. Mercury. Environmental exposure. Environmental pollution. Child. Pregnancy.<\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t
\n\t\t\t\t\t\t\t
\n\t\t\t\n\t\t\t\t\n\t\t\t\t\tBACK to theses and dissertations\t\t\t\t<\/span>\n\n\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t<\/path><\/svg>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Introdu\u00e7\u00e3o: A exposi\u00e7\u00e3o ambiental a metais em \u00e1reas urbanas tem sido associada a desfechos do nascimento tais como: prematuridade, baixo<\/p>","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[91],"tags":[],"class_list":["post-14735","post","type-post","status-publish","format-standard","hentry","category-teses-e-dissertacoes"],"_links":{"self":[{"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/posts\/14735","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/comments?post=14735"}],"version-history":[{"count":0,"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/posts\/14735\/revisions"}],"wp:attachment":[{"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/media?parent=14735"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/categories?post=14735"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pipaufrj.me.ufrj.br\/en\/wp-json\/wp\/v2\/tags?post=14735"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}